Health

Understanding HIV-1 Leukopaks

Have you heard of human HIV-1 leukopaks?  Research on HIV-1, a world-wide infectious disease, is an on-going process. And, for those researchers who need infected lymphocytes, our leukopaks offer the perfect solution. All of our leukopaks come with information on the source of the peripheral cells including gender, ethnicity, date of diagnosis and current medications and past treatments.  Each leukopak comes from a single healthy donor whose cells are concentrated during collection and isolated from the peripheral blood.

The cells are removed from one donar using an aphresis machine.  After the leukocytes are filtered out of the blood, the remaining product is returned to the donar.  These cell lines are tested after collection for mycoplasma, bacteria, yeast, and fungi.  They are also tested in any other ways that the client needs to complete their research.  Before becoming a donar, the intended donars are tested for a variety of conditions that could make their cells unusable.  They are als required to sign a consent form for both the testing and the donations.  Leukopaks represent cells that are collected over several sessions from the same donar.  This is necessary to obtain the concentration of cells.

HIV-1 is an active form of the virus that causes AIDS.  The HIV viruses cause the lymphatic system to reduce the number of CD4 cells in the body.  This inactivates T-cells that protect against a group of tumor causing infections.  Without adequate levels of CD4 cells, the person invaded by HIV will develop a number of diseases that normally the body protects itself against.  On average, a person infected with HIV that is active will survive about one year without treatment.  More than one type of HIV virus causes this disease.  But, HIV-1 remains wide spread and is a good subject to study the effects of the disease, reactions of treatments and for development of potential vaccines.

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